In Excel, you can remove a directory by following these steps:

1. Open the File Explorer.
2. Locate the directory you want to delete.
3. Right-click on the directory and select "Delete" from the context menu.

If you want to delete a directory and all of its contents, you can use the "Shift + Delete" keyboard shortcut. This will bypass the Recycle Bin, so the deleted files will be permanently gone.